can H+/H2O be used instead of NaOH in gabriels pthalamide process
NaOH cannot be replaced by H+/H2O
Gabriel Phthalamide is a nucleophilic substitution reaction.
The purpose of the base is to deprotonate the phthalimide to generate a stronger nucleophile
to displaces the halide ion from alkyl halide.
Gabriel Phthalamide is a nucleophilic substitution reaction.
The purpose of the base is to deprotonate the phthalimide to generate a stronger nucleophile
to displaces the halide ion from alkyl halide.