In and experiment the tails of mice were surgically removed generation after generation, yet tailless mice never appeared in the progeny.
Give reason
This was the famous experiment performed by August Weismann. He proposed that somatic cell plays no role in heredity, and are not inherited, only the germ cell pass on traits and which is not affected by any traits the somatic cell acquire during the lifetime of an organism. This is the reason why after cutting the tails of mice for 22 generations, not a single tailless mice appeared in the progeny