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 Q.Describe in Six Steps in the Clotting of blood ..

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Dear Student,

Blood Coagulation
  • Clotting is required to prevent excessive loss of blood from the body.
  • Blood clot − formed by threads of fibrin in which formed elements are trapped
  • Prothrombin (inactive form)thrombin (active form)
  • Fibrinogen (inactive form) fibrin (active form)
  • Mechanism of coagulation is a cascade of reactions involving several clotting factors.
  • Calcium ions play an important role in blood clotting mechanism.
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  • The injured tissue cells and platelets which disintigrate at the site of wound release a substance thrombokinase.
  • The thrombokinase acts as an enzyme and with the help of the calcium ions present in the plasma, it converts a substance prothrombin(inactive) of plasma into thrombin(active).
  • Thrombin in the presence of calcium ions, reacts with the insoluble fibrinogen of the plasma to convert it into soluble fibrin.
  • Fibrin is a solid substance that forms threads. These microscopic threads of fibrin are sticky and form a mesh(network) at the wound.
  • Blood cells are trapped in the network of the fibrin, the network the shrinks and squeezes out the rest of the plasma which is in the form of clear liquid, the serum.
  • The solid mass which is left behind is called clot(or thrombus).
     
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 thank u rajrishabh138

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