ADH increse reabsorption of water from tubule (decrese urine output ) and also it increse GFR due to contracts vessel( increse urine output). How this contradictory effect is possible? U have given answer but i can't understand pl explain me

Dear student,Vasopressin produced dose-dependent antidiuretic and natriuretic responses. Hormone infused at both rates increased the clearance of sodium, but only the higher dose caused a significant increase in GFR..It appears, therefore, that increases in GFR may have a role in the natriuretic response to both hormone so it has contradictory effect.