Can ELISA be used for molecular diagnosis of a genetic disorder such as phenylketonuria - Biology - Human Health and Disease

Question

Can ELISA be used for molecular diagnosis of a genetic disorder
such as phenylketonuria?

Pratik Das · Accepted Answer

hi !!
ELISA is based on the ability of low molecular weights
antibodies to couple with enzymes, to produce enzymatically active
immunological conjugates We can detect the immune reaction with
histochemical staining techniques becase antibody component is
involved in the immune reaction and the conjugated enzyme can be
used for staining reaction using an appropriate susbstrate This
test detects the presence of antigen and antibodies in the serum of
a patient
On the other hand, phenylketonuria is due to the excess of
phenylalanine in blood
Hencxe, ELISA cannot detect as such genetic disorders
Cheers!!!

Can ELISA be used for molecular diagnosis of a genetic disorder such as phenylketonuria?