Column I	Column II
A. Southern blotting	I. Running of DNA fragments on gel
B. Gel electrophoresis	II. Cutting of DNA into fragments
C. Cleavage	III. Transfer of DNA fragment from gel to  nitrocellulose disc
D. DNA probing	IV. Searching for desired DNA fragments

(a) A- IV, B-I, C-II, D-II
(b) A-II, B-I, C-IV, D-III
(c) A-IV, B-I, C-III, D-II
(d) A-I, B-IV, C-II, D-III
 

The correct option is (a).

• Southern blotting is a method used to detect specific DNA molecules from a mixture of DNA molecules.
• Gel electrophoresis is the method of running DNA fragments on the gel. 
• Cleavage refers to the cutting of DNA o get the DNA  fragments. 
• DNA probing is the transfer of electrophoresed DNA fragments from gel to some other medium. 

Hope this information will clear your doubts about the topic.   
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