Difference between hormone action in protein hormone and steroid hormone
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A hormone is a chemical messenger that regulates physiological processes in living organisms. It is secreted by a gland.
Mechanism of Hormone Action
Hormones exhibit their effects only after binding to their specific receptors located in the target tissues to form hormone-receptor complex.
Membrane-bound receptors: Present on the cell membrane of the target cell
Intracellular receptors: Present inside the target cell
This specific reaction leads to biochemical changes in the target tissue, and regulates its metabolism and physiological changes.
Mechanism of action of protein hormones :
Hormones interacting with the membrane-bound receptors (insulin, glucagon, pituitary and hypothalamic hormones) do not enter the cells, but generate secondary messengers (e.g., cyclic AMP, IP3). These secondary messengers regulate cellular metabolism.
Mechanism of action of steroid hormones:
Hormones interacting with the intracellular receptors (e.g., steroid hormones, iodothyronines) regulate gene expression by the interaction of the hormone-receptor complex with the genome.
Hope this information will clear your doubts about the mechanism of action of protein and steroid hormones.
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