difference between nucleosome and chromatosome

Dear student.

The DNA (negatively charged) winds around histone octamer (positively charged) to form nucleosome. One nucleosome has approx. 200 bp of DNA. Nucleosomes in a chromatin resemble beads present on strings.

Chromatosome is a nucleosome that consists of a histone octamer, one molecule of linker histone such as Histone H1 and about 166bp of DNA. The linker histone is a binding agent, that holds the DNA together preventing its release.


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