difference between smooth and rough ER
The most basic difference between RER and SER is the presence of ribosomes. When ribosomes attach to the surface of an ER, it gives a characteristic rough appearance; hence it is called Rough ER. On the other hand, a smooth ER does not have ribosomes on its surface.
The other major difference between the smooth endoplasmic reticulum and rough endoplasmic reticulum are summarized below:
|Rough Endoplasmic Reticulum (RER)||Smooth Endoplasmic Reticulum (SER)|
|It possesses ribosomes attached to its membrane.||It does not have ribosomes on its membrane.|
|Formed of cisternae and a few tubules.||Formed of vesicles and tubules.|
|It participates in the synthesis of enzymes and proteins.||Synthesises glycogen, lipids and steroids.|
|It helps in the formation of lysosomes.||Gives rise to Spherosomes/ Oleosomes|
|It is internal and connected with the nuclear envelope.||It is peripheral and may be connected to plasmalemma.|
|Ribophorins are present and help ribosomes attach to ER||Devoid of Ribophorins.|
|It might develop from the nuclear envelope||Develops from Rough Endoplasmic Reticulum.|
|Provides proteins and lipids for Golgi apparatus.||Provides vesicles for cis-face of Golgi apparatus.|
Rough and smooth ER?(endoplasmic reticulum)?differ?in that the?rough ER?has ribosomes on it. ...?Smooth ER?does not have ribosomes and is where steroids are made, which is why there is a lot of?smooth ER?in cells of the the adrenal gland and sex organs which produce steroid hormones such as estrogen and testosterone.