Explain the mechanism of hormone action in short.

Dear Student,
Hormones produce their effect on target tissues by binding to specific proteins called hormone receptors located in target tissue only.
Hormone receptors which are present on the cell membrane of the target cells are called membrane-bound receptors. The receptors present inside the target cell is called intracellular receptors, mostly nuclear receptors (present in the nucleus). 

Each receptor is specific to only one hormone and hence receptors are specific. Hormone-Receptor complex formation leads to certain biochemical changes in a target tissue. Target tissue metabolism & hence physiological functions are regulated by hormones.

Hormones that interact with membrane-bound receptors generally do not enter the target cell instead it generates second messengers (e.g cyclic AMP, Ca+2, IP 3) which in turn regulates cellular metabolism.
Hormones which interact with intracellular receptors (e.g iodothyronines, steroid hormones, etc) mostly regulate gene expression or chromosome function by the interaction of hormone-receptor complex with the genome.

Regards.




 

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