Explain this para
Solution:
MHC stands for Major Histocompatibility complex. It is a group of genes on short arm of chromosome 6 in humans and codes the MHC antigens. These antigens are the ones which determine whether the graft will be accepted or rejected by the body as know antibodies are produced against the antigens of a cell or organ introduced in the body. Major as well as minor histocompatibility antigens are also called transplantation antigens as they mediate rejection of grafts between two genetically different individuals. Monozygotic human twins have the same histocompatibility molecules on their cells, and they can accept transplants of tissue from each other.
MHC stands for Major Histocompatibility complex. It is a group of genes on short arm of chromosome 6 in humans and codes the MHC antigens. These antigens are the ones which determine whether the graft will be accepted or rejected by the body as know antibodies are produced against the antigens of a cell or organ introduced in the body. Major as well as minor histocompatibility antigens are also called transplantation antigens as they mediate rejection of grafts between two genetically different individuals. Monozygotic human twins have the same histocompatibility molecules on their cells, and they can accept transplants of tissue from each other.
Histocompatibility molecules of one individual act as antigens when introduced into a different individual.
HLA (human leukocyte antigen) is a protein or marker that has to be matched between the patient and the donor during transplantation.