"Fluid mosaic model of cell membrane" was given by singer and nicolson. Explain the structure with the help of a diagram.

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The structure of plasma membrane was proposed by Singer and Nicolson in 1972. It is widely accepted as fluid mosaic model. According to this model-

• The cell membrane is composed of a lipid bilayer, with a polar head towards the outer side, and hydrophobic tails towards the inner side. So, the non-polar,  hydrophobic tail is protected from the aqueous environment.
• Proteins and carbohydrates are also present in the membrane.
• Membrane proteins can be integral (lying buried in the membrane) or peripheral (lying on the surface of the membrane).
• The fluid mosaic model shows the quasi-fluid nature of lipids enables lateral movement of proteins within the bilayer.
• Fluidity is the measure of the ability of the membrane to allow movement within itself.
• Fluid nature of the membrane is important for cell division, cell growth, the formation of intercellular junctions, secretion, and endocytosis.

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