How are acidophils and basophils antigonistic

Dear student,
Acidophils and basophils are not antagonistic. Acidophils and basophils two kinds of cells in the anterior pituitary. They stain differently in the presence of acidic and basic dye due to which they are named acidophils and basophils. Acidophils include two kinds of cells somatotroph and lactotroph. Basophils include cells corticotroph, thyrotroph, and gonadotroph. Isoelectric point in basophil cell's protein is basic and isoelectric point in acidophil's protein is acidic. Acidophilic cells are found in the antero-lateral-area and the basophilic cells are found in the posterior-central- area.

Regards

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Acidophils

Cells that contain the polypeptide hormones:

  • Somatotropes which produce growth hormone
  • Lactotropes which produce prolactin
Basophils

Cells that contain the glycoprotein hormones:

  • Thyrotropes which produce thyroid stimulating hormone
  • Gonadotropes which produce luteinizing hormone or follicle-stimulating hormone
  • Corticotropes which produce adrenocorticotrophic hormone

Due the high carbohydrate content of the hormones within acidophils, they also stain bright purple with PAS stains.

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Acidophils are cells that contain polypeptide hormones - Somatotropes and Lactotropes.
Basophils are cells that contain glycoprotein hormones - Thyrotropes, Gonadotropes and Corticotropes.
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