How do the antimicrobial control the microbial disease ?!.. 
[Kindly don't give links.. as I've already checked other answers on merit related to this one.. :D]

Dear student.

Different antimicrobial drugs such as antiviral, antifungal, antibiotics have different mode of action. Some may target cell wall of pathogen, some may target particular enzyme necessary for the replication of microbes, some drugs may cause stress inside the cell. I am providing you the mode of action of antibiotics.

Antibiotics act by blocking certain biochemical pathways which are essential for the survival of bacteria-like cell wall formation, protein synthesis etc. For example: Penicillin is an antibiotic. It blocks the formation of cell wall in bacteria, which makes bacteria weak and ultimately results in death of bacteria. However, antibiotics cannot be used against viruses. This is because, viruses do not possess any cellular machinery of their own to function. In fact, they get integrated with the host cell and use machinery of the host to survive. They are non-living outside the host and they have very few biochemical pathways of their own. Hence, it is difficult to find virus-specific targets. 

Regards.

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