How does ATP synthesises ? Explanation with diagram .

Dear student,

Oxidative phosphorylation is the mechanism of ATP synthesis in mitochondrion during respiration. In this process, proton gradient across the membrane is used to synthesise  ATP  from  ATP synthase.

The energy of oxidation-reduction is utilised for the production of proton gradient needed for the synthesis of ATP this is why this  process is called oxidative phosphorylation.

When the electrons are transferred from one carrier to the other in the electron transport chain, protons get pumped into the inter-membrane space of the mitochondria creating a proton gradient across the membrane. When these protons pass through the ATP synthase enzyme complex, ATP gets synthesised. This enzyme complex consists of F 0 and F 1 components. The F 1 headpiece is a peripheral membrane protein complex and contains the site for ATP synthesis from ADP and inorganic phosphate. F 0 component is a part of membrane protein complex, which acts as a channel for crossing of the protons from inner mitochondrial membrane to the mitochondrial matrix. For every two protons passing through F 0 –F 1 complex, synthesis of one ATP molecule takes place.

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