How many molecules of last electron acceptor in ETS is required if one molecule of isocitrate is a substrate during aerobic respiration?

Ans: four (4) Electron transport system is the final step of release of the ATP from the FAdh2 and NaDPH and these results in the formation of three and two ATP molecules respectively.   These electron acceptor in electron transport system is molecular oxygen. This accepts electron and gets reduced to form water.   Now for every molecule of isocitrate, there is 4 rounds of electron transport system should go on. As a result four molecules of oxygen is required.