How pcr is different from dna replication

Dear student,both replication and PCR are chain reactions but differences are:-DNA replication is carried out at body temperature (37 degree C in humans) with the help of complex machinery while PCR reaction utilizes temperature cycles (with extremes of 70-90C) to cause denaturation and annealing of DNA strands,There are many DNA polymerases in eukaryotes while in PCR, thermostable DNA polymerases derived from bacteria or archaea are used (eg. Taq polymerase),,Whole genomic DNA is replicated in the body while in the PCR reaction, the polymerase used has a much shorter half-life, and is only efficient for much smaller fragments of DNA.Regards.

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