In this question the answer key says option 2 but it should be option 1 as in chloride shift there is influx of cl- ions into RBC


Plz clarify it soon.

Dear student,

Ans. Option (1) is correct: Influx of Cl- ions into RBC.

Chloride shift is a process that takes place when CO2 enters blood from the tissues and gets converted into bicarbonate ions by carbonic anhydrase, leading to accumulation of bicarbonate ions in the RBCs. Thus,chloride shift could be defined as the diffusion of Chloride anions (Cl-) from blood plasma into cytoplasm of RBCs as well as diffusion of  bicarbonate anions (HCO3-) out of cytoplasm of erythrocytes (RBCs) into the blood plasma. This serves to maintain the electrochemical neutality in RBCs or  maintaining the blood pH.
These bicarbonate and chloride ions are transported across the red blood cell membrane in opposite directions by the bicarbonate-chloride carrier protein. 

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