Please explain this to me...

Dear Student,
Please find your answer below to the asked query:

Succinic acid is the odd one out. As in this step only energy formation is there like GTP or ATP.
Krebs Cycle: It is a step in cellular aerobic respiration. It is a series of chemical reaction that breaks down glucose for energy. It is also known as Citric Acid Cycle or Tricarboxylic Acid Cycle.
The over view of the cycle is mentioned below:
  • Acetyl group condenses with oxaloacetic acid and water to yield citric acid (catalysed by the enzyme citrate synthase)
  • Citrate isomerises into isocitrate
  • Two successive decarboxylation steps follow, leading to the formation of α ketoglutaric acid, followed by succinyl CoA
  • This is followed by the conversion of succinyl CoA into succinic acid (substrate level phosphorylation). In a coupled reaction, GTP is converted into GDP, simultaneously synthesising ATP from ADP.
  • Conversion of one molecule of pyruvate into acetyl CoA yields 1 molecule of CO2 and 1 NADH.
  • One Krebs cycle yields 2 CO2 + 3 NADH + 1 FADH2 + 1 ATP
  • Overall equation:
  • For continued oxidation of acetyl CoA in TCA 2 things are required:
    • Continued replenishment of oxaloacetic acid
    • Regeneration of NAD+ and FAD+ from NADH and FADH2 respectively.


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