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Dear Student,

Ans. Primarily mediated by IgM antibodies.

Anamnestic response or secondary immune response is a release of antibodies when our immune system is encountered with the same kind of pathogen. When our body encounters a particular pathogen, our brain makes a memory of that pathogen and our immune system start secreting antibodies against that pathogen to kill it. So that when we again encounter that pathogen our body already has a antibodies for that pathogen to kill it. This kind of response is known as a anamnestic response and our body produce it to protect itself from that pathogen.

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