The negatively charged DNA is wrapped around the positively charged histone octamer to form a structure called nucleosome . A typical nucleosome contains 200 bp of DNA helix. Nucleosome constitue the repeating unit of a structure in nucleus called chromatin, thread -like statined (coloured) bodies seen in nucleus. The nucleosomes in chromatin are seen as 'beads-on-string' structure when viewed under electron microscope (EM)

Theoretically, how many such beads, (nucleosomes) do you imagine are present in a mammalian cell?

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It is not possible to comment on the number of nucleosomes present in mammalian cells. However, in case of humans, a diploid cell nucleus contains approximately 30 million nucleosomes, arranged as beads on DNA.
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