the principle site of acidification of tubular fluid is
a)urinary bladder
b)aldosterone sensitive distal nephron
c)PCT
d)loop of henle
Dear Student,
Please find below the solution to the asked query:
According to the given options, the answer would be Option (c) PCT.
Maximum amount of H+ secretion occurs in the PCT (80-85%), mainly to reabsorb filtered bicarbonate. Here, H+ secretion increases only 3-4 fold. On the contrary, H+ secretion increases to upto 1000 times in late distal tubule and collecting duct, but they account for only 5-10% of the total H+ secretion. This is important for acidification of the urine.It decreases the pH of tubular fluid to 4.5. Therefore, the answer otherwise should be collecting duct.
Hope this information will clear your doubts about the topic.
If you have any more doubts just ask here on the forum and our experts will try to help you out as soon as possible.
Regards
Please find below the solution to the asked query:
According to the given options, the answer would be Option (c) PCT.
Maximum amount of H+ secretion occurs in the PCT (80-85%), mainly to reabsorb filtered bicarbonate. Here, H+ secretion increases only 3-4 fold. On the contrary, H+ secretion increases to upto 1000 times in late distal tubule and collecting duct, but they account for only 5-10% of the total H+ secretion. This is important for acidification of the urine.It decreases the pH of tubular fluid to 4.5. Therefore, the answer otherwise should be collecting duct.
Hope this information will clear your doubts about the topic.
If you have any more doubts just ask here on the forum and our experts will try to help you out as soon as possible.
Regards