what diseases can be detected by elisa and pcr .please give me a seperated proper list
ELISA and PCR are both used for the detection of various infectious diseases. ELISA is based on the antigen antibody reactions, while PCR detects the nucleic acid of the organism. Hence, both these can be used to detect any infectious pathogen. ELISA tests can also be used to detect allergic and autoimmune diseases while PCR test cannot be used in these.
But PCR based detection has various advantages over ELISA, as it is much more specific, fast and can detect the pathogen at very low levels; while ELISA can detect the pathogen once antibodies are formed. So, PCR detection can help us in detecting the infection at an early stage.
Some of the pathogens detected by PCR are:
- HIV, which causes AIDS
- Hepatitis B and C (cause liver cancer)
- Human Papillomavirus, (cause cervical cancer)
- Chlamydia trachomatis, (cause infertility in women)
- Neisseria gonorrhoeae, (pelvic inflammatory disease)
- Cytomegalovirus
- Mycobacterium tuberculosis (causes tuberculosis)
Some of the pathogens detected by ELISA are:
- Influenza (causes common cold)
- HIV (causes AIDS)
- Salmonella typhi, (causes typhoid)
- West Nile virus
- Hepatitis C (causes liver cancer)
- Autoimmune diseases
- Allergies