What is haldane effect ?
Dear student,
Hemoglobin is a protein found in the red blood cells (RBCs). The hemoglobin helps in the gaseous exchange inside the body. It transports the oxygen from the lungs to the tissues and carries carbon dioxide from the tissues to the lungs.
Haldane Effect- It describes how binding of oxygen to hemoglobin promotes the release of carbon dioxide. It states the oxygen and carbon dioxide compete for hemoglobin occupancy. Following are the two ways of Haldane effect-
Regards
Hemoglobin is a protein found in the red blood cells (RBCs). The hemoglobin helps in the gaseous exchange inside the body. It transports the oxygen from the lungs to the tissues and carries carbon dioxide from the tissues to the lungs.
Haldane Effect- It describes how binding of oxygen to hemoglobin promotes the release of carbon dioxide. It states the oxygen and carbon dioxide compete for hemoglobin occupancy. Following are the two ways of Haldane effect-
- The affinity of the protein (hemoglobin) is reduced for the carbon dioxide when the hemoglobin is bound to oxygen.
- The oxygen binding to the hemoglobin makes hemoglobin a more acidic molecule that results in the release of free hydrogen ions. Thus, it pushes the reversible equilibrium between bicarbonate and carbon dioxide in the direction of carbon dioxide to facilitates the conversion of bicarbonate to carbon dioxide in the pulmonary circulation that enhances carbon dioxide elimination.
Regards