when do person need repeated blood transfusion - Biology - Human Health and Disease

Question

when do person need repeated blood transfusion??

Riffat Jahan · Accepted Answer

People need repeated blood transfusions in many diseased
conditions such as when suffering from sickle cell anaemia,
Thalassemia, blood cancer, etc In most of these conditions,
abnormal conditions occur in blood cells So, to survive the
patients have to obtainn healthy blood from the donors
For example in Sickle cell anaemia, an abnormal type of
haemoglobin called haemoglobin S is formed Hemoglobin S changes the
shape of red blood cells to sickle-like or crescents It is a
disease caused by a mutation in the amino acid at 6th position in
the beta chain of hemoglobin which results in replacement of
glutamine by valine The major characteristics of this disease are
anemia (less functional RBCs) and a tendency of the red blood cells
to to deliver oxygen become less