why acantamoeba is considered as an dangerous one? and are the problems faced by the people due to acant amoeba

Acanthamoeba can cause a serious, most often deadly, infection of the brain and spinal cord called Granulomatous Encephalitis (GAE). ... Skin infections do not necessarily lead to disseminated disease. Disseminated infection. Acanthamoeba can also cause skin lesions and/or disseminated infection.