write the difference between eli lily insulin and the one produced by human pancreas?
Dear Student.
Please find below the solution to the asked query.
Humulin is a brand name of human insulin produced by Eli Lilly company of America by the help of recombinant DNA technology.The two chains of insulin are separately synthesised in two E.coli. Further, these two chains are isolated from the bacterium and joined by creating disulphide bonds to create human insulin called humulin.
Mature insulin consists of only two peptide chains − A and B that are linked by disulphide bonds. This mature insulin is a functional hormone. It helps in the uptake of glucose from blood and maintains its optimum level.
In mammals including humans, Insulin is produced as pro hormone that consists of 3 peptide chains − A, B, and C. This pro hormone needs to be processed before it becomes fully mature (functional), so that it can be used to cure diabetes in humans.
Pro-enzyme insulin ​Mature insulin​
Hope this information will clear your doubts about the topic.
If you have any more doubts just ask here on the forum and our experts will try to help you out as soon as possible.
Regards.
Please find below the solution to the asked query.
Humulin is a brand name of human insulin produced by Eli Lilly company of America by the help of recombinant DNA technology.The two chains of insulin are separately synthesised in two E.coli. Further, these two chains are isolated from the bacterium and joined by creating disulphide bonds to create human insulin called humulin.
Mature insulin consists of only two peptide chains − A and B that are linked by disulphide bonds. This mature insulin is a functional hormone. It helps in the uptake of glucose from blood and maintains its optimum level.
In mammals including humans, Insulin is produced as pro hormone that consists of 3 peptide chains − A, B, and C. This pro hormone needs to be processed before it becomes fully mature (functional), so that it can be used to cure diabetes in humans.
Pro-enzyme insulin ​Mature insulin​
Hope this information will clear your doubts about the topic.
If you have any more doubts just ask here on the forum and our experts will try to help you out as soon as possible.
Regards.