Depletion of ozon molecule in the strusfare due to Share with your friends Share 0 N Dubey answered this Dear student. The cause of ozone layer depletion is human activity, specifically, human-made chemicals that contain chlorine or bromine. Regard 0 View Full Answer Tanmay . answered this Chlorofluorocarbons 2 Mariam answered this When chlorine and bromine atoms come in contact with ozone in the stratosphere , they destroy ozone molecules. 1 Jyoti Mungikar answered this Please find this answer 0 Vanraj answered this Please find this answer 0 Mahi Aggarwal answered this chlorofluorocarbons 0