Diagrammatically explain the formation of thymine dimer by non-ionizing radion source
Solution:
Usually there are four bases in DNA among which two (cytosine and thymine) are most vulnerable to UV radiation. UV rays can change the properties of bases by oxidizing and can alter them resulting in mutation in the gene.
Usually there are four bases in DNA among which two (cytosine and thymine) are most vulnerable to UV radiation. UV rays can change the properties of bases by oxidizing and can alter them resulting in mutation in the gene.
Non-ionizing radiation like UV can cause DNA damage leading to neoplastic transformation.
UV rays contain less energy other than ionising radiations and never eject electrons but, these rays are highly mutagenic and are potentially active in causing mutagens. The nitrogen bases: purines and pyrimidines readily absorbs UV rays, thereby resulting in bond formation between pyrimidine molecules of the same strand called as pyrimidine dimers. In this most cases, this occurs with cytosine and thymine dimer formation. Thus, the process of replication gets blocked.
UV rays contain less energy other than ionising radiations and never eject electrons but, these rays are highly mutagenic and are potentially active in causing mutagens. The nitrogen bases: purines and pyrimidines readily absorbs UV rays, thereby resulting in bond formation between pyrimidine molecules of the same strand called as pyrimidine dimers. In this most cases, this occurs with cytosine and thymine dimer formation. Thus, the process of replication gets blocked.