difference between glycogenesis, glycogenolysis and glyconeogenesis?
What is the difference between Glycogenolysis and Gluconeogenesis?
• Glyconeogenesis is the production of glucose from non-carbohydrate sources, whereas glycogenolysis is the process of glycogen breakdown.
• During glycogenolysis, glycogen is broken down to form the glucose-6-phosphate, and during gluconeogenesis, molecules such as amino acids and lactic acids convert into glucose.
What is the difference between Glycolysis and Gluconeogenesis?
• The three essentially irreversible reactions of the glycolic pathway are circumvented in gluconeogenesis pathway by four bypass reactions.
• Gluconeogenesis is an anabolic pathway while glycolysis is a catabolic pathway.
• Glycolysis is an exergonic pathway, thus yielding two ATPs per glucose. Gluconeogenesis requires coupled hydrolysis of six phosphoanhydride bonds (four from ATP and two from GTP) in order to direct the process of glucose formation.
• Gluconeogenesis occurs mainly in the liver whereas glycolysis occurs in muscles and other various tissues.
• Glycolysis is a process of catabolizing glucose and other carbohydrates while gluconeogenesis is a process of synthesizing sugars and polysaccharides.
• First seven reactions in the gluconeogenesis pathway occur by simple reversal of the corresponding reactions in glycolysis pathway.
• Glycolysis uses two ATP molecules but generates four. Therefore, the net yielding ATPs per glucose are two. On the other hand, glyconeogenesis consumes six ATP molecules and synthesize one glucose molecule.