for the formation of the leading strand and the lagging strand RNA primer formed by RNA primase is used rite - Biology - Molecular Basis of Inheritance

Question

for the formation of the leading strand and the lagging strand RNA
primer formed by RNA primase is used rite ?
the only difference is that :
1)lagging strand is of continuos synthesis by lagging strand of
discontinuous synthesis
2)leading strand has a polarity of 3'-5' so
the new strand base paired in 5'-3'
direction
but the lagging strand has polarity of
5'-3'direction how does the fragments form ?

Jahirul Mazumder · Accepted Answer

Dear student

The main enzyme involved in DNA replication is the DNA-dependent
DNA polymerase This enzyme catalyses the polymerisation of
deoxynucleotides along the 5′ → 3′ direction, and
hence, replication is continuous along the 3′ → 5′
strand (leading strand) and discontinuous along the template, i e ,
the 5′ → 3′ direction (lagging strand)

Okazaki fragments are short DNA segments on the lagging strand,
formed in the 5’ – 3’ direction, starting from
RNA primers A separate RNA primer is needed for the synthesis of
each Okazaki fragment These discontinuously synthesized fragments
are later joined by the enzyme DNA ligase

The polarity of template strand is always 3' to 5' and while that
of coding stand is 5' to 3'

Regards