How the formation of urine takes place?
Glomerular Filteration;
It is the first step in urine formation and occurs when the blood enters the glomerulus. The capillaries of the glomerulus offer resistance to the flow of the blood and thus the blood pressure is setup. Due to this glomerular blood pressure water and dissolved slats glucose drugs urea and uric acid moves from the glomerulus to the inside of the Bowman’s capsule. The process by which the fluid is separated from the blood in the glomerulus is called the glomerular filtration process and the filtered substances are called glomerular filtrate, in glomerular filtration process large molecules, blood and platelets are unable to pass through the capillary walls.
Tubular re-absorption:
Re-absorption of water and nutrients such as glucose, amino acids, and some salts like NaCl which are useful to the body occurs from the proximal tubule into the blood, this is selective re-absorption because excess of salts, urea and uric acid are not absorbed. Water is reabsorbed along the whole length of the nephron especially in the loop of Henle.
Tubular secretions:
It is the mechanism by which substances are removed from the blood and are directly added to the tubular fluids. Hydrogen ion, ammonium and drugs such as penicillin are some of the substances that move from the blood into the distal tubule of nephron. Secretions keep the blood from becoming acidic.Tubular secretion helps to maintain ionic and acid balance of body fluids.