in neutral protein , we should have equal amount of acidic as well as basic amino acid am i right ?
Dear student.
You are correct, but not accurately.
The exact explanation is, "it is the overall charge on the protein (conferred by amino acids), that will determine whether it will be acidic, basic or neutral. The charge is conferred by the ionizable groups on the side chains of their amino acids, as well as amino and carboxyl groups. Charge on protein is also dependent on the pH of the solution. A protein will have no net charge, at its isoelectric point (pI) is defined as the pH at which a protein has no net charge. If pH > pI , a protein will have net negative charge, and if pH < pI, the protein will have net positive charge.
There are amino acids such as arginine (Arg), lysine (Lys), and histidine (His) which bears basic side chains at neutral pH.
There are amino acids have acidic side chains at neutral pH, Examples: aspartic acid and glutamic acid.
Regards.
You are correct, but not accurately.
The exact explanation is, "it is the overall charge on the protein (conferred by amino acids), that will determine whether it will be acidic, basic or neutral. The charge is conferred by the ionizable groups on the side chains of their amino acids, as well as amino and carboxyl groups. Charge on protein is also dependent on the pH of the solution. A protein will have no net charge, at its isoelectric point (pI) is defined as the pH at which a protein has no net charge. If pH > pI , a protein will have net negative charge, and if pH < pI, the protein will have net positive charge.
There are amino acids such as arginine (Arg), lysine (Lys), and histidine (His) which bears basic side chains at neutral pH.
There are amino acids have acidic side chains at neutral pH, Examples: aspartic acid and glutamic acid.
Regards.