Name the genes that constitute an operon. how does operon get switched on in the presence of lactose ?
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Genes constituting lac operon:
All genes involved in lac operon are required for metabolism of lactose. Lactose acts as an inducer for lac operon since it regulates the switching on and off of the operon.
Regulation in Presence of Inducer
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​Please find below the solution to the asked query
Genes constituting lac operon:
Gene | Nature | Function |
i gene | Inhibitor | It codes for repressor of lac operon. |
z gene | Structural | It codes for β-galactosidase. |
y gene | Structural | It codes for permease, which increases the permeability of cell to β-galactosidase. |
a gene | Structural | It codes for transacetylase. |
All genes involved in lac operon are required for metabolism of lactose. Lactose acts as an inducer for lac operon since it regulates the switching on and off of the operon.
Regulation in Presence of Inducer
- Inducer binds with the protein product of gene i (repressor) and inactivates it.
- This inactivated repressor is unable to inactivate RNA polymerase enzyme and z, y, and a genes synthesise their respective mRNA, which in turn gets translated to form β-galactosidase, permease, and transacetylase.
- In presence of all these enzymes, the metabolism of lactose proceeds in a normal manner.
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