We have seen that cells possess a special enzyme to remove uracil from DNA What do you suppose would - Biology - Molecular Basis of Inheritance

Question

We have seen that cells possess a special enzyme to remove uracil
from DNA What do you suppose would happen if the uracil groups were
not removed?

Abhishek Mudgal · Answer

DNA polymerases are the enzymes that build DNA in
cells During DNA replication (copying), most DNA polymerases can
“check their work” with each base that they add This
process is called proofreading If the polymerase
detects that a wrong (incorrectly paired) nucleotide has been
added, it will remove and replace the nucleotide right away, before
continuing with DNA synthesis^11start superscript, 1, end
superscript
<img alt=
"Proofreading: 1 DNA polymerase adds a new base to the 3' end of the growing, new strand (The template has a G, and the polymerase incorrectly adds a T rather than a C to the new strand ) 2 Polymerase detects that the bases are mispaired 3 Polymerase uses 3' to 5' exonuclease activity to remove the incorrect T from the 3' end of the new strand "
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"https://cdn%20kastatic%20org/ka-perseus-images/fd025fc7b765b7df394990fa014b93b70c94eba6%20png"
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Direct reversal: Some DNA-damaging chemical
reactions can be directly "undone" by enzymes in the cell
Excision repair: Damage to one or a few bases
of DNA is often fixed by removal (excision) and replacement of the
damaged region In base excision repair, just the
damaged base is removed In nucleotide excision
repair, as in the mismatch repair we saw above, a patch of
nucleotides is removed
Double-stranded break repair: Two major
pathways, non-homologous end joining and homologous recombination,
are used to repair double-stranded breaks in DNA (

We have seen that cells possess a special enzyme to remove uracil from DNA. What do you suppose would happen if the uracil groups were not removed?