what is Haemophilia ?

I just know dat its a Recessive Gene Disorder,

my question is dat what actually happens to a patient when he suffers from it?

Haemophilia is an X linked genetic disorder in which the person suffering does not develop a proper blood clotting mechanism.

 

Haemophilia is a congenital disease or genetically inherited disease. It is caused by the deficiency of Factor VIII, an important clotting factor.

The mutation in the genome leads to this deficiency. It occurs mainly in males.The gene for this factor is carried on the X-Chromosome. This gene appears in the normal (dominant) and the mutant (recessive form).

Females have X X chromosomes while males have only one X with Y chromosome, so for a female to get affected by haemophilia she has to have the mutant gene on both the X chromosomes while males may be affected if the carry it on the one X chromosome.

It has been observed that if only one X chromosome is carrying the mutant gene, that female does not have the disease, but she is a carrier. This proves that the X linked trait of haemophilia is recessive.

 

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 Haemophilia ?

 is a group of hereditary genetic disorders that impair the body's ability to control blood clotting or coagulation, which is used to stop bleeding when a blood vessel is broken.

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 bt how does a gene gets affected is that a virus or something else which happens to affect it?

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