what is RNA interference technique of cellular defence explain with an example.
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RNA interference is a genetic mechanism of eukaryotes that suppresses gene expression and in which double-stranded RNA cleaved into small fragments initiates the degradation of a complementary messenger RNA sequence.
FOR EXAMPLE-
Several nematodes parasitize a wide variety of plants and animals including human beings. A nematode Meloidogyne incognita infects the roots of tobacco plants and causes a great reduction in yield. A novel strategy was adopted to prevent this infestation which was based on the process of RNA interference (RNAi). RNAi takes place in all eukaryotic organisms (also in this case) as a method of cellular defense. This method involves the silencing of a specific mRNA due to a complementary dsRNA molecule that binds to and prevents translation of the mRNA(silencing). The source of this complementary RNA could be from an infection by viruses having RNA genomes or mobile genetic elements (transposons) that replicate via an RNA intermediate.
regards
RNA interference is a genetic mechanism of eukaryotes that suppresses gene expression and in which double-stranded RNA cleaved into small fragments initiates the degradation of a complementary messenger RNA sequence.
FOR EXAMPLE-
Several nematodes parasitize a wide variety of plants and animals including human beings. A nematode Meloidogyne incognita infects the roots of tobacco plants and causes a great reduction in yield. A novel strategy was adopted to prevent this infestation which was based on the process of RNA interference (RNAi). RNAi takes place in all eukaryotic organisms (also in this case) as a method of cellular defense. This method involves the silencing of a specific mRNA due to a complementary dsRNA molecule that binds to and prevents translation of the mRNA(silencing). The source of this complementary RNA could be from an infection by viruses having RNA genomes or mobile genetic elements (transposons) that replicate via an RNA intermediate.
regards