what is the scheme given by embden,meyerhof parnas ?
The Scheme of Glycolysis was given by Embden, Meyerhof and Parnas.
Glycolysis ( Glycos − Sugar, Lysis − Splitting) Breakdown of glucose to pyruvic acid by partial oxidation. Common pathway for aerobic and anaerobic cellular respiration. Occurs in the cytoplasm of a cell. Present in all living organisms. In plants , sucrose is converted into glucose. H exokinase: Enzyme that phosphorylates glucose to produce glucose − 6 − phosphate. 2 ATPs are utilised in two steps:
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Glucose → Glucose − 6 − phosphate (1 ATP)
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Fructose − 6 − phosphate → fructose 1, 6 − bisphosphate (1 ATP)
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Fructose 1, 6 bisphosphate splits into glyceraldehyde − 3 − phosphate and dihydroxy acetone phosphate.
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Glyceraldehyde − 3 − phosphate converts into two molecules of 1, 3 bisphosphoglycerate (BPGA), with subsequent conversion of NAD + to NADH + H + .
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4 ATPs are yielded in two steps:
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BPGA → PGA (1 × 2 = 2 ATPs)
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Phosphoenol pyruvate → Pyruvic acid (1 × 2 =2 ATPs)
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Net ATPs produced = 4 (produced) − 2 (consumed) = 2 ATPs